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Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells.
We have analyzed the modulation of amyloid beta-protein precursor (APP) gene expression in human umbilical vein endothelial cells (HUVEC). The level of the APP mRNA transcripts increased as HUVEC reached confluency. In confluent culture the half-life of the APP mRNA was 4 hr. Treatment of the cells...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
1989
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298115/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2508093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.19.7606 |
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