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Effects of angiotensin type 1 receptor blockade on arginine and ADMA synthesis and metabolic pathways in fawn-hooded hypertensive rats

Background. The fawn-hooded hypertensive (FHH) rat develops spontaneous glomerulosclerosis that is ameliorated by inhibition of the angiotensin II type 1 receptor (AT-1). Since kidney damage is associated with nitric oxide (NO) deficiency, we investigated how AT-1 antagonism influenced nitric oxide...

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Detalhes bibliográficos
Main Authors: Chen, Gin-Fu, Wagner, Laszlo, Sasser, Jennifer M., Zharikov, Sergey, Moningka, Natasha C., Baylis, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980996/
https://ncbi.nlm.nih.gov/pubmed/20484304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfq272
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