Protective actions of nebivolol on chronic nitric oxide synthase inhibition-induced hypertension and chronic kidney disease in the rat: a comparison with angiotensin II receptor blockade

BACKGROUND. Nitric oxide (NO) deficiency contributes to chronic kidney disease (CKD) progression and hypertension. The β-blocker, nebivolol (N), also enhances NO production, and we studied whether N attenuates CKD and hypertension caused by chronic NO synthase inhibition (CNOSI). METHODS. Male Sprag...

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Bibliographic Details
Main Authors: Moningka, Natasha C., Tsarova, Tatsiana, Sasser, Jennifer M., Baylis, Chris
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289897/
https://ncbi.nlm.nih.gov/pubmed/21856762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfr449
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