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A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting.
Embryonal rhabdomyosarcomas (malignant pediatric tumors of striated muscle origin) have been shown to arise from cells that are clonally isodisomic for loci on chromosome 11p. We determined the parental origin of alleles in this genomic region in familial and sporadic cases of this disease and found...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298088/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2798419/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.19.7480 |
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