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Mice with altered α-actinin-4 expression have distinct morphologic patterns of glomerular disease

Mutations in ACTN4, encoding the actin-binding protein α-actinin-4, cause a form of familial focal segmental glomerulosclerosis. We had developed two strains of transgenic mice with distinct alterations in the expression of α-actinin-4. One strain carried a human disease-associated mutation in murin...

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Detalhes bibliográficos
Main Authors: Henderson, Joel M., al-Waheeb, Salah, Weins, Astrid, Dandapani, Savita V., Pollak, Martin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980842/
https://ncbi.nlm.nih.gov/pubmed/18185509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.ki.5002751
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