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Mice with altered α-actinin-4 expression have distinct morphologic patterns of glomerular disease
Mutations in ACTN4, encoding the actin-binding protein α-actinin-4, cause a form of familial focal segmental glomerulosclerosis. We had developed two strains of transgenic mice with distinct alterations in the expression of α-actinin-4. One strain carried a human disease-associated mutation in murin...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980842/ https://ncbi.nlm.nih.gov/pubmed/18185509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.ki.5002751 |
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