A carregar...
Crystal structure of the actin-binding domain of α-actinin-4 Lys255Glu mutant implicated in focal segmental glomerulosclerosis
Mutations in α-actinin-4 have been linked to familial focal segmental glomerulosclerosis (FSGS), a common renal disorder in humans, and produce an apparent increase in the actin-binding affinity of α-actinin-4 in vitro. One of the mutations in particular, Lys255Glu, falls in the middle of the actin-...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2255586/ https://ncbi.nlm.nih.gov/pubmed/18164029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.11.084 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|