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Cellular FLIP can substitute for the herpes simplex virus type 1 latency-associated transcript gene to support a wild-type virus reactivation phenotype in mice

Latency-associated transcript (LAT) deletion mutants of herpes simplex virus type 1 (HSV-1) have reduced reactivation phenotypes. Thus, LAT plays an essential role in the latency-reactivation cycle of HSV-1. We have shown that LAT has antiapoptosis activity and demonstrated that the chimeric virus,...

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Detaylı Bibliyografya
Asıl Yazarlar: Jin, Ling, Carpenter, Dale, Moerdyk-Schauwecker, Megan, Vanarsdall, Adam L, Osorio, Nelson, Hsiang, Chinhui, Jones, Clinton, Wechsler, Steven L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980827/
https://ncbi.nlm.nih.gov/pubmed/18989818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13550280802216510
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