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Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice
Muscular dystrophy results in the progressive wasting and necrosis of skeletal muscle. Glucocorticoids such as prednisone have emerged as a front-line treatment for many forms of this disease. Recently, Debio-025, a cyclophilin inhibitor that desensitizes the mitochondrial permeability pore and subs...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980760/ https://ncbi.nlm.nih.gov/pubmed/20637615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nmd.2010.06.016 |
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