Functional and Molecular Effects of Arginine Butyrate and Prednisone on Muscle and Heart in the mdx Mouse Model of Duchenne Muscular Dystrophy

BACKGROUND: The number of promising therapeutic interventions for Duchenne Muscular Dystrophy (DMD) is increasing rapidly. One of the proposed strategies is to use drugs that are known to act by multiple different mechanisms including inducing of homologous fetal form of adult genes, for example utr...

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Main Authors: Guerron, Alfredo D., Rawat, Rashmi, Sali, Arpana, Spurney, Christopher F., Pistilli, Emidio, Cha, Hee-Jae, Pandey, Gouri S., Gernapudi, Ramkishore, Francia, Dwight, Farajian, Viken, Escolar, Diana M., Bossi, Laura, Becker, Magali, Zerr, Patricia, de la Porte, Sabine, Gordish-Dressman, Heather, Partridge, Terence, Hoffman, Eric P., Nagaraju, Kanneboyina
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2010
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888587/
https://ncbi.nlm.nih.gov/pubmed/20574530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011220
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