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RNA structure, not sequence, determines the 5' splice-site specificity of a group I intron.

The group I self-splicing introns act at exon-intron junctions without recognizing a particular sequence. In order to understand splice-site selection, we have developed an assay system based on the Tetrahymena ribozyme to allow the study of numerous 5'-splice-site variants. Cleavage at the cor...

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Sonraí Bibleagrafaíochta
Main Authors: Doudna, J A, Cormack, B P, Szostak, J W
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1989
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC298070/
https://ncbi.nlm.nih.gov/pubmed/2678103
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