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RNA structure, not sequence, determines the 5' splice-site specificity of a group I intron.
The group I self-splicing introns act at exon-intron junctions without recognizing a particular sequence. In order to understand splice-site selection, we have developed an assay system based on the Tetrahymena ribozyme to allow the study of numerous 5'-splice-site variants. Cleavage at the cor...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298070/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2678103/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.19.7402 |
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