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A modified fluorescent intercalator displacement assay for RNA ligand discovery

Fluorescent intercalator displacement (FID) is a convenient and practical tool for identifying new nucleic-acid-binding ligands. The success of FID is based on the fact that it can be fashioned into a versatile screening assay for assessing the relative binding affinities of compounds to nucleic aci...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Asare-Okai, Papa Nii, Chow, Christine S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980581/
https://ncbi.nlm.nih.gov/pubmed/20863807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.09.020
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