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Hypoxia downregulates p53 but induces apoptosis and enhances expression of BAD in cultures of human syncytiotrophoblasts

Hypoxia is commonly assigned a role in the placental dysfunction characteristic of preeclampsia and intrauterine growth restriction. We previously showed that hypoxia upregulates p53 and enhances apoptosis in primary cultures of human cytotrophoblasts. Here we tested the hypothesis that hypoxia also...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Baosheng, Longtine, Mark S., Sadovsky, Yoel, Nelson, D. Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980304/
https://ncbi.nlm.nih.gov/pubmed/20810912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00154.2010
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