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cGMP-induced differentiation of the promyelocytic cell line HL-60.
cGMP is a second messenger that mediates numerous metabolic events; in the present work a role in myeloid cell differentiation was demonstrated. Nitroprusside and NaNO2, which activate cytosolic guanylate cyclase and increase the intracellular cGMP concentration, induced granulocytic differentiation...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1989
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC298018/ https://ncbi.nlm.nih.gov/pubmed/2550930 |
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