cGMP-induced differentiation of the promyelocytic cell line HL-60.
cGMP is a second messenger that mediates numerous metabolic events; in the present work a role in myeloid cell differentiation was demonstrated. Nitroprusside and NaNO2, which activate cytosolic guanylate cyclase and increase the intracellular cGMP concentration, induced granulocytic differentiation...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1989
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298018/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2550930/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.18.7174 |
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