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Evidence that v-src and v-fps gene products use a protein kinase C-mediated pathway to induce expression of a transformation-related gene.

Induction of the transformation-related gene 9E3 by the v-src and v-fps gene products (v-Src and v-Fps) is blocked in chicken embryo fibroblasts depleted of protein kinase C (PKC). PKC agonists induce 9E3 gene expression. Protein kinase inhibitors block v-Src- and v-Fps-induced 9E3 gene expression w...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Spangler, R, Joseph, C, Qureshi, S A, Berg, K L, Foster, D A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297983/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2550927/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.18.7017
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