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The common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function.

A conserved noncatalytic domain SH2 (for src homology region 2) is located immediately N terminal to the kinase domains of all cytoplasmic protein-tyrosine kinases. We found that the wild-type v-fps SH2 domain stimulated the enzymatic activity of the adjacent kinase domain 10-fold and functioned as...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Koch, C A, Moran, M, Sadowski, I, Pawson, T
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1989
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC362491/
https://ncbi.nlm.nih.gov/pubmed/2685548
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