Retroviral vector-mediated high-efficiency expression of adenosine deaminase (ADA) in hematopoietic long-term cultures of ADA-deficient marrow cells.

Two recombinant retroviral vectors encoding the cDNA of the human adenosine deaminase (ADA; EC 3.5.4.4) gene and the bacterial neomycin resistance (Neo) gene have been used to transduce bone marrow cells obtained from four patients affected by the ADA-deficient variant of severe combined immunodefic...

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Detalhes bibliográficos
Main Authors: Bordignon, C, Yu, S F, Smith, C A, Hantzopoulos, P, Ungers, G E, Keever, C A, O'Reilly, R J, Gilboa, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC297923/
https://ncbi.nlm.nih.gov/pubmed/2549545
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