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Marked increases in hepatic NAD(P)H:oxidoreductase gene transcription and mRNA levels correlated with a mouse chromosome 7 deletion.

The NAD(P)H:menadione oxidoreductase gene (Nmo-1) codes for a quinone reductase (also called DT diaphorase; EC 1.6.99.2) believed to play a central role in protection against oxidative stress. We have studied mice with a radiation-induced chromosomal deletion involving the albino locus (c) on chromo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Petersen, D D, Gonzalez, F J, Rapic, V, Kozak, C A, Lee, J Y, Jones, J E, Nebert, D W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297913/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2505256/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.17.6699
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