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The Unusual Cosubstrate Specificity of NQO2: Conservation Throughout the Amniotes and Implications for Cellular Function

Human Quinone Reductase 2 (NQO2) is a pharmacological target and has appeared in numerous screening efforts as an off-target interactor with kinase-targeted drugs. However the cellular functions of NQO2 are not known. To gain insight into the potential cellular functions of NQO2, we have carried out...

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Autori principali: Faiza Islam, Kevin K. Leung, Matthew D. Walker, Shahed Al Massri, Brian H. Shilton
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-04-01
Serie:Frontiers in Pharmacology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fphar.2022.838500/full
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