Xenopus oocyte germinal-vesicle breakdown induced by [Val12]Ras is inhibited by a cytosol-localized Ras mutant.

The GTPase-activating protein (GAP) has been postulated to function either as a negative regulator or as a possible target protein of Ras in mammalian cells and Xenopus oocytes. Ras must be localized in the plasma membrane of vertebrate cells to function, but GAP is localized in the cytosol. To test...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Gibbs, J B, Schaber, M D, Schofield, T L, Scolnick, E M, Sigal, I S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297898/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2672000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.17.6630
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