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Xenopus oocyte germinal-vesicle breakdown induced by [Val12]Ras is inhibited by a cytosol-localized Ras mutant.

The GTPase-activating protein (GAP) has been postulated to function either as a negative regulator or as a possible target protein of Ras in mammalian cells and Xenopus oocytes. Ras must be localized in the plasma membrane of vertebrate cells to function, but GAP is localized in the cytosol. To test...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Gibbs, J B, Schaber, M D, Schofield, T L, Scolnick, E M, Sigal, I S
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1989
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297898/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2672000/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.17.6630
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