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Xenopus oocyte germinal-vesicle breakdown induced by [Val12]Ras is inhibited by a cytosol-localized Ras mutant.

The GTPase-activating protein (GAP) has been postulated to function either as a negative regulator or as a possible target protein of Ras in mammalian cells and Xenopus oocytes. Ras must be localized in the plasma membrane of vertebrate cells to function, but GAP is localized in the cytosol. To test...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Gibbs, J B, Schaber, M D, Schofield, T L, Scolnick, E M, Sigal, I S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297898/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2672000/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.17.6630
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