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Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

The signal transducer and activator of transcription 3 (STAT3) contributes to cardioprotection by ischemic pre- and postconditioning. Mitochondria are central elements of cardioprotective signaling, most likely by delaying mitochondrial permeability transition pore (MPTP) opening, and STAT3 has rece...

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Detalhes bibliográficos
Main Authors: Boengler, Kerstin, Hilfiker-Kleiner, Denise, Heusch, Gerd, Schulz, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978889/
https://ncbi.nlm.nih.gov/pubmed/20960209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-010-0124-1
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