Clinical Expression of LRRK2 G2019S Mutations in the Elderly

Mutations in the leucine-rich repeat kinase 2 gene (LRRK2, PARK8) are the most commonly identified monogenic etiology of Parkinson disease (PD). Over-represented in the Ashkenazi Jewish (AJ) population, these mutations are transmitted in an autosomal dominant manner with age-dependent reduced penetr...

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Bibliographic Details
Main Authors:	Luciano, Marta San, Lipton, Richard B., Wang, Cuiling, Katz, Mindy, Zimmerman, Molly E., Sanders, Amy E., Ozelius, Laurie J., Bressman, Susan B., Saunders-Pullman, Rachel
Format:	Artigo
Language:	Inglês
Published:	2010
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2978804/ https://ncbi.nlm.nih.gov/pubmed/20721910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.23330
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Clinical Expression of LRRK2 G2019S Mutations in the Elderly

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