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Clinical Expression of LRRK2 G2019S Mutations in the Elderly
Mutations in the leucine-rich repeat kinase 2 gene (LRRK2, PARK8) are the most commonly identified monogenic etiology of Parkinson disease (PD). Over-represented in the Ashkenazi Jewish (AJ) population, these mutations are transmitted in an autosomal dominant manner with age-dependent reduced penetr...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978804/ https://ncbi.nlm.nih.gov/pubmed/20721910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.23330 |
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