Increased Mitochondrial Fatty Acid Oxidation Is Sufficient to Protect Skeletal Muscle Cells from Palmitate-induced Apoptosis

The mechanisms underlying the protective effect of monounsaturated fatty acids (e.g. oleate) against the lipotoxic action of saturated fatty acids (e.g. palmitate) in skeletal muscle cells remain poorly understood. This study aimed to examine the role of mitochondrial long-chain fatty acid (LCFA) ox...

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Detalhes bibliográficos
Main Authors: Henique, Carole, Mansouri, Abdelhak, Fumey, Gwladys, Lenoir, Veronique, Girard, Jean, Bouillaud, Frederic, Prip-Buus, Carina, Cohen, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978610/
https://ncbi.nlm.nih.gov/pubmed/20837491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.170431
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