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A fast, efficient and sequence-independent method for flexible multiple segmental isotope labeling of RNA using ribozyme and RNase H cleavage

Structural information on RNA, emerging more and more as a major regulator in gene expression, dramatically lags behind compared with information on proteins. Although NMR spectroscopy has proven to be an excellent tool to solve RNA structures, it is hampered by the severe spectral resonances overla...

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Main Authors: Duss, Olivier, Maris, Christophe, von Schroetter, Christine, Allain, Frédéric H.-T.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978384/
https://ncbi.nlm.nih.gov/pubmed/20798173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq756
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