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Small nucleolar RNA interference in Trypanosoma brucei: mechanism and utilization for elucidating the function of snoRNAs

Expression of dsRNA complementary to small nucleolar RNAs (snoRNAs) in Trypanosoma brucei results in snoRNA silencing, termed snoRNAi. Here, we demonstrate that snoRNAi requires the nuclear TbDCL2 protein, but not TbDCL1, which is involved in RNA interference (RNAi) in the cytoplasm. snoRNAi depends...

詳細記述

保存先:
書誌詳細
主要な著者: Gupta, Sachin Kumar, Hury, Avraham, Ziporen, Yaara, Shi, Huafang, Ullu, Elisabetta, Michaeli, Shulamit
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2010
主題:
RNA
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978370/
https://ncbi.nlm.nih.gov/pubmed/20601683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq599
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