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The beta-amyloid protein precursor of Alzheimer disease has soluble derivatives found in human brain and cerebrospinal fluid.

In this study, we use antisera to synthetic beta-amyloid protein precursor (beta APP) peptides to identify, in human brain and cerebrospinal fluid (CSF), soluble approximately 125- and approximately 105-kDa derivatives of the beta APP that lack the carboxyl terminus of the full-length, membrane-asso...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Palmert, M R, Podlisny, M B, Witker, D S, Oltersdorf, T, Younkin, L H, Selkoe, D J, Younkin, S G
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1989
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297834/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2503832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.16.6338
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