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Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

Progressive cerebral deposition of extracellular filaments composed of the beta-amyloid protein (beta AP) is a constant feature of Alzheimer disease (AD). Since the gene on chromosome 21 encoding the beta AP precursor (beta APP) is not known to be altered in AD, transcriptional or posttranslational...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Selkoe, D J, Podlisny, M B, Joachim, C L, Vickers, E A, Lee, G, Fritz, L C, Oltersdorf, T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1988
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282182/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3140239/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7341
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