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Antibodies to non-beta regions of the beta-amyloid precursor protein detect a subset of senile plaques.

A central unresolved issue in Alzheimer's disease is the origin of the extracellular amyloid beta protein (A beta P) found in senile plaques and its relationship to the dystrophic neurites that intimately surround it. Here the presence and distribution within senile plaques of various epitopes...

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Detalhes bibliográficos
Main Authors: Joachim, C., Games, D., Morris, J., Ward, P., Frenkel, D., Selkoe, D.
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886178/
https://ncbi.nlm.nih.gov/pubmed/1704190
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