Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients.

The amyloid beta-protein is deposited in senile plaques and the cerebrovasculature in Alzheimer disease (AD). Since it is derived from proteolytic processing of its parent protein, the amyloid beta-protein precursor (APP), we investigated whether levels of the secreted forms of APP are altered in ce...

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Detalhes bibliográficos
Main Authors: Van Nostrand, W E, Wagner, S L, Shankle, W R, Farrow, J S, Dick, M, Rozemuller, J M, Kuiper, M A, Wolters, E C, Zimmerman, J, Cotman, C W
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC48699/
https://ncbi.nlm.nih.gov/pubmed/1557359
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