Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients.

The amyloid beta-protein is deposited in senile plaques and the cerebrovasculature in Alzheimer disease (AD). Since it is derived from proteolytic processing of its parent protein, the amyloid beta-protein precursor (APP), we investigated whether levels of the secreted forms of APP are altered in ce...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Van Nostrand, W E, Wagner, S L, Shankle, W R, Farrow, J S, Dick, M, Rozemuller, J M, Kuiper, M A, Wolters, E C, Zimmerman, J, Cotman, C W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48699/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557359/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.2551
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