Identification and structural analysis of C-terminally truncated collapsin response mediator protein-2 in a murine model of prion diseases

BACKGROUND: Prion diseases are fatal neurodegenerative disorders that accompany an accumulation of the disease-associated form(s) of prion protein (PrP(Sc)) in the central nervous system. The neuropathological changes in the brain begin with focal deposits of PrP(Sc), followed by pathomorphological...

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Hlavní autoři: Shinkai-Ouchi, Fumiko, Yamakawa, Yoshio, Hara, Hideyuki, Tobiume, Minoru, Nishijima, Masahiro, Hanada, Kentaro, Hagiwara, Ken'ichi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978134/
https://ncbi.nlm.nih.gov/pubmed/20961402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-8-53
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