Tracking and clarifying differential traits of classical- and atypical L-type bovine spongiform encephalopathy prions after transmission from cattle to cynomolgus monkeys

Classical- (C-) and atypical L-type bovine spongiform encephalopathy (BSE) prions cause different pathological phenotypes in cattle brains, and the disease-associated forms of each prion protein (PrPSc) has a dissimilar biochemical signature. Bovine C-BSE prions are the causative agent of variant Cr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hagiwara, Ken’ichi, Sato, Yuko, Yamakawa, Yoshio, Hara, Hideyuki, Tobiume, Minoru, Okemoto-Nakamura, Yuko, Sata, Tetsutaro, Horiuchi, Motohiro, Shibata, Hiroaki, Ono, Fumiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522098/
https://ncbi.nlm.nih.gov/pubmed/31095605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216807
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