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Lewis Acid-Catalyzed Conjugate Additions of Silyloxyallenes: A Selective Solution to the Intermolecular Rauhut–Currier Problem

[Image: see text] Silyloxyallenes serve as highly useful α-acylvinyl anion equivalents. These latent allenolates undergo conjugate additions to alkylidene malonates in the presence of 10 mol% Sc(OTf)(3). The reaction delivers intermolecular Rauhut–Currier products in excellent yields and regioselect...

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Autori principali: Reynolds, Troy E., Binkley, Michael S., Scheidt, Karl A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977949/
https://ncbi.nlm.nih.gov/pubmed/18476709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol800745q
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