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High-Throughput, Sensitive Quantification of Repopulating Hematopoietic Stem Cell Clones
Retroviral vector-mediated gene therapy has been successfully used to correct genetic diseases. However, a number of studies have shown a subsequent risk of cancer development or aberrant clonal growths due to vector insertion near or within proto-oncogenes. Recent advances in the sequencing technol...
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| Main Authors: | , , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Microbiology (ASM)
2010
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2977897/ https://ncbi.nlm.nih.gov/pubmed/20844053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01355-10 |
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