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A High-Throughput Method for Cloning and Sequencing Human Immunodeficiency Virus Type 1 Integration Sites

Integration of retroviral DNA is nonspecific and can occur at many sites throughout chromosomes. However, the process is not uniformly distributed, and both hot and cold spots for integration exist. The mechanism that determines target site specificity is not well understood. Because of the nonspeci...

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Autors principals: Kim, Sanggu, Kim, Yein, Liang, Teresa, Sinsheimer, Janet S., Chow, Samson A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1642152/
https://ncbi.nlm.nih.gov/pubmed/16971446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01737-06
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