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Nuclear Export of Human Papillomavirus Type 31 E1 Is Regulated by Cdk2 Phosphorylation and Required for Viral Genome Maintenance

The initiator protein E1 from human papillomavirus (HPV) is a helicase essential for replication of the viral genome. E1 contains three functional domains: a C-terminal enzymatic domain that has ATPase/helicase activity, a central DNA-binding domain that recognizes specific sequences in the origin o...

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Detalhes bibliográficos
Main Authors: Fradet-Turcotte, Amélie, Moody, Cary, Laimins, Laimonis A., Archambault, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977856/
https://ncbi.nlm.nih.gov/pubmed/20844047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01445-10
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