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Human Papillomaviruses Activate the ATM DNA Damage Pathway for Viral Genome Amplification upon Differentiation

Human papillomaviruses (HPV) are the causative agents of cervical cancers. The infectious HPV life cycle is closely linked to the differentiation state of the host epithelia, with viral genome amplification, late gene expression and virion production restricted to suprabasal cells. The E6 and E7 pro...

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Detalles Bibliográficos
Autores principales: Moody, Cary A., Laimins, Laimonis A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745661/
https://ncbi.nlm.nih.gov/pubmed/19798429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000605
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