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Human Papillomaviruses Activate the ATM DNA Damage Pathway for Viral Genome Amplification upon Differentiation

Human papillomaviruses (HPV) are the causative agents of cervical cancers. The infectious HPV life cycle is closely linked to the differentiation state of the host epithelia, with viral genome amplification, late gene expression and virion production restricted to suprabasal cells. The E6 and E7 pro...

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Detalhes bibliográficos
Main Authors: Moody, Cary A., Laimins, Laimonis A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745661/
https://ncbi.nlm.nih.gov/pubmed/19798429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000605
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