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Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone.

Islet amyloid polypeptide (IAPP) is a 37-amino acid peptide found in the pancreatic amyloid deposits of type II (non-insulin-dependent) diabetic patients and insulinomas. We previously reported the nucleotide sequence of a human cDNA, which indicated that IAPP is a C-terminally amidated peptide deri...

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Bibliografski detalji
Glavni autori: Nishi, M, Chan, S J, Nagamatsu, S, Bell, G I, Steiner, D F
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC297705/
https://ncbi.nlm.nih.gov/pubmed/2668946
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