Formulation, Release Characteristics and Bioavailability Study of Oral Monolithic Matrix Tablets Containing Carbamazepine

This study examined the release of carbamazepine (CBZ) from hydrophobic (Compritol® 888 ATO) and hydrophilic-hydrophobic matrix combination (Compritol® 888 ATO-hydroxpropyl methylcellulose, HPMC). Hydrophobic matrix tablets were prepared by hot fusion technique, while hydrophilic-hydrophobic matrix...

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Detalhes bibliográficos
Main Authors: Barakat, Nahla S., Elbagory, Ibrahim M., Almurshedi, Alanood S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2008
Assuntos:
Research Article/Theme: Oral Controlled Release Development and Technology/Guest Editors: Stephen A. Howard and Jian-Xin Li
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977049/
https://ncbi.nlm.nih.gov/pubmed/18686038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9108-y
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