Controlled Release Matrix Tablets of Zidovudine: Effect of Formulation Variables on the In Vitro Drug Release Kinetics

The purpose of this research was to design oral controlled release (CR) matrix tablets of zidovudine (AZT) using hydroxypropyl methylcellulose (HPMC), ethyl cellulose (EC) and carbopol-971P (CP) and to study the effect of various formulation factors on in vitro drug release. Release studies were car...

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Hlavní autoři: Ravi, Punna Rao, Kotreka, Udaya Kanth, Saha, Ranendra Narayan
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2008
Témata:
Research Article/Themed Issue: Oral Controlled Release Development and Technology/Guest Editors: Stephen Howard and Jian-Xin Li
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976876/
https://ncbi.nlm.nih.gov/pubmed/18446496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-007-9030-8
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