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Studies on Formulation Development of Mucoadhesive Sustained Release Itraconazole Tablet Using Response Surface Methodology

The purpose of this research was to prepare and evaluate sustained release mucoadhesive tablets of Itraconazole. It is practically insoluble in aqueous fluids hence its solid dispersion with Eudragit E100 was prepared by spray drying. This was formulated in matrix of hydrophilic mucoadhesive polymer...

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Detalhes bibliográficos
Main Authors: Madgulkar, Ashwini, Kadam, Shivajirao, Pokharkar, Varsha
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977043/
https://ncbi.nlm.nih.gov/pubmed/18770050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9119-8
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