Studies on Formulation Development of Mucoadhesive Sustained Release Itraconazole Tablet Using Response Surface Methodology

The purpose of this research was to prepare and evaluate sustained release mucoadhesive tablets of Itraconazole. It is practically insoluble in aqueous fluids hence its solid dispersion with Eudragit E100 was prepared by spray drying. This was formulated in matrix of hydrophilic mucoadhesive polymer...

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Hlavní autoři: Madgulkar, Ashwini, Kadam, Shivajirao, Pokharkar, Varsha
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2008
Témata:
Research Article/Theme: Oral Controlled Release Development and Technology/Guest Editors: Stephen A. Howard and Jian-Xin Li
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977043/
https://ncbi.nlm.nih.gov/pubmed/18770050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9119-8
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