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The Aging-Associated Enzyme CLK-1 is a Member of the Carboxylate-Bridged Diiron Family of Proteins
The aging-associated enzyme CLK-1 is proposed to be a member of the carboxylate-bridged diiron family of proteins. To evaluate this hypothesis and characterize the protein, we expressed soluble mouse CLK-1 (MCLK1) in E. coli as a heterologous host. Using Mössbauer and EPR spectroscopy, we establishe...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2976817/ https://ncbi.nlm.nih.gov/pubmed/20923139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101475z |
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