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The Inflammatory Response Induced by Aspartic Proteases of Candida albicans Is Independent of Proteolytic Activity

The secretion of aspartic proteases (Saps) has long been recognized as a virulence-associated trait of the pathogenic yeast Candida albicans. In this study, we report that different recombinant Saps, including Sap1, Sap2, Sap3, and Sap6, have differing abilities to induce secretion of proinflammator...

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Main Authors: Pietrella, Donatella, Rachini, Anna, Pandey, Neelam, Schild, Lydia, Netea, Mihai, Bistoni, Francesco, Hube, Bernhard, Vecchiarelli, Anna
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976325/
https://ncbi.nlm.nih.gov/pubmed/20713630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00789-10
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