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The Inflammatory Response Induced by Aspartic Proteases of Candida albicans Is Independent of Proteolytic Activity

The secretion of aspartic proteases (Saps) has long been recognized as a virulence-associated trait of the pathogenic yeast Candida albicans. In this study, we report that different recombinant Saps, including Sap1, Sap2, Sap3, and Sap6, have differing abilities to induce secretion of proinflammator...

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Bibliografische gegevens
Hoofdauteurs: Pietrella, Donatella, Rachini, Anna, Pandey, Neelam, Schild, Lydia, Netea, Mihai, Bistoni, Francesco, Hube, Bernhard, Vecchiarelli, Anna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976325/
https://ncbi.nlm.nih.gov/pubmed/20713630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00789-10
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