Candida albicans Releases Soluble Factors That Potentiate Cytokine Production by Human Cells through a Protease-Activated Receptor 1- and 2-Independent Pathway

The innate immune system recognizes pathogen-associated molecular patterns (PAMPs) through pattern recognition receptors (PRR) and transduces downstream signaling to activate the host defense. Here we report that in addition to direct PAMP-PRR interactions, live Candida albicans cells can release so...

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Detalhes bibliográficos
Main Authors: Cheng, Shih-Chin, Chai, Louis Y. A., Joosten, Leo A. B., Vecchiarelli, Anna, Hube, Bernhard, Van Der Meer, Jos W., Kullberg, Bart Jan, Netea, Mihai G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798204/
https://ncbi.nlm.nih.gov/pubmed/19858310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01041-09
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