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A Candida albicans Mannoprotein Deprived of Its Mannan Moiety Is Efficiently Taken Up and Processed by Human Dendritic Cells and Induces T-Cell Activation without Stimulating Proinflammatory Cytokine Production

Mannoproteins are cell wall components of pathogenic fungi and play major virulence and immunogenic roles with both their mannan and protein moieties. The 65-kDa mannoprotein (MP65) of Candida albicans is a β-glucanase adhesin recognized as a major target of the human immune response against this fu...

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Detalhes bibliográficos
Main Authors: Pietrella, Donatella, Lupo, Patrizia, Rachini, Anna, Sandini, Silvia, Ciervo, Alessandra, Perito, Stefano, Bistoni, Francesco, Vecchiarelli, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519437/
https://ncbi.nlm.nih.gov/pubmed/18591233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00669-08
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